Sweet Home Alabama (2002)

directed by Andy Tennant
featuring Reese Witherspoon, Josh Lucas, Patrick Dempsey, Candice Bergen, Mary Kay Place

Transformers: Dark of the Moon (2011)

directed by Michael Bay
featuring Shia LaBeouf, Rosie Huntington-Whiteley, Josh Duhamel, John Turturro, Tyrese Gibson, Patrick Dempsey, Frances McDormand, John Malkovich

With Honors (1994)

directed by Alek Keshishian
featuring Joe Pesci, Brendan Fraser, Moira Kelly, Patrick Dempsey, Josh Hamilton

Enchanted (2007)

directed by Kevin Lima
featuring Amy Adams, Patrick Dempsey, James Marsden, Timothy Spall, Idina Menzel

Bridget Jones's Baby (2016)

directed by Sharon Maguire
featuring Renée Zellweger, Colin Firth, Patrick Dempsey, Jim Broadbent, Gemma Jones

Grey's Anatomy: Season 04 (2007)

Grey's Anatomy: Season 01 (2005)

Can't Buy Me Love (1987)

directed by Steve Rash
featuring Patrick Dempsey, Amanda Peterson, Courtney Gains, Seth Green, Tina Caspary

Made of Honor (2008)

directed by Paul Weiland
featuring Patrick Dempsey, Michelle Monaghan, Kevin McKidd, Kathleen Quinlan, Sydney Pollack

Freedom Writers (2007)

directed by Richard LaGravenese
featuring Hilary Swank, Scott Glenn, Imelda Staunton, Patrick Dempsey, Mario, April Lee Hernandez

Grey's Anatomy: Season 02 (2005)

Mobsters (1991)

directed by Michael Karbelnikoff
featuring Christian Slater, Patrick Dempsey, Richard Grieco, Costas Mandylor, F. Murray Abraham

Grey's Anatomy: Season 09 (2012)

Jeremiah (2000)

directed by Harry Winer
featuring Patrick Dempsey, Klaus Maria Brandauer, Oliver Reed, Leonor Varela, Michael Cronin

Grey's Anatomy: Season 10 (2013)

Scream 3 (2000)

directed by Wes Craven
featuring David Arquette, Neve Campbell, Courteney Cox, Patrick Dempsey, Scott Foley

20,000 Leagues Under the Sea (1997)

directed by Rod Hardy, Ron Hardy
featuring Michael Caine, Patrick Dempsey, Mia Sara, Bryan Brown, Adewale Akinnuoye-Agbaje

Lucky 7 (2003)

directed by Harry Winer
featuring Kimberly Williams-Paisley, Brad Rowe, Patrick Dempsey

Brother Bear 2: The Moose Are on the Loose (2006)

directed by Benjamin Gluck
featuring Patrick Dempsey, Mandy Moore, Wanda Sykes, Jeremy Suarez, Rick Moranis

Coupe De Ville (1990)

directed by Joe Roth
featuring Patrick Dempsey, Arye Gross, Daniel Stern, Annabeth Gish, Rita Taggart

In the Mood (1987)

directed by Phil Alden Robinson
featuring Patrick Dempsey, Beverly D'Angelo, Talia Balsam, Michael Constantine, Betty Jinnette

Winning: The Racing Life of Paul Newman (2015)

directed by Adam Carolla
featuring Adam Carolla, Mario Andretti, Patrick Dempsey, Jay Leno

Flypaper (2011)

directed by Rob Minkoff
featuring Patrick Dempsey, Ashley Judd, Tim Blake Nelson, Mekhi Phifer, Pruitt Taylor Vince

A Season in Purgatory (1996)

directed by David Greene
featuring Patrick Dempsey, Blair Brown, Brian Dennehy, Sherilyn Fenn, Craig Sheffer, David Marshall Grant

Hugo Pool (1997)

directed by Robert Downey, Sr.
featuring Alyssa Milano, Patrick Dempsey, Cathy Moriarty, Malcolm McDowell, Robert Downey, Jr.