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Topical application of drugs to the eye is the most popular and well-accepted route of administration in various eye disorders. The bioavailability of ophthalmic drugs is, however, very poor due to efficient protective mechanisms of the eye like blinking, baseline and reflex lachrymation, and drainage remove rapidly foreign substances, including drugs, from the surface of the eye.Ophthalmic drug delivery is one of the most interesting and challenging endeavors facing by the pharmaceutical scientist. The anatomy, physiology, ...

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