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A benchmark review on how specific nutrients or adverse nutritional states impact the components of the IGF (Insulin-like Growth Factor) system and affect human health and disease. The authors describe the fundamentals of the IGF system, explain its basic mechanisms of action, illuminate its essential role in physical development across the life span, and highlight the link between normal and abnormal cellular growth resulting in tumor formation. They also fully examine the clinical aspects of nutrition and IGF, from pre- ...

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