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With the current emphasis in cancer research on oncogenes and suppressor genes, and on autocrine factors and their receptors, it is easy to conclude that the "whole story"can be read in the cancer cell "per se." No one would deny that the tremendous recent advances in describing the molecular and cellular alterations in cancer cells have greatly added to our understanding of neoplasia. But, learning how to translate the meaning of these alterations into ways of treating and, better yet, preventing cancer will require at ...

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