Antibiotic Production from Soil Isolates by Fermentation

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The term antibiotic appeared as early as 1928 in the French microbiological literature as antibiosis. The phenomenon of antagonism between living organisms was frequently observed even since 1877, when Pasteur and Joubert noticed that aerobic bacteriaantagonized the growth of Bacillus anthracis. However, the world in its present restrictive meaning, "a chemical substance derived from microorganisms, which has the capacity of inhibiting growth and even destroying other organisms in dilute solutions" was introduced by Selman ...

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